Decoding Genomic Dark Matter
We design novel synthetic promoters to control cell-type selective gene expression for our clients
Our Platform
By mining the genome using our bioinformatics platform we discover and re-purpose natural gene regulatory elements, creating customised gene expression systems to:
Improve human health
Creating highly selective and controllable promoters and gene expression cassettes for novel gene and cell therapy systems
Improving the efficiency of biologics production by increasing protein yields in upstream manufacturing processes
Engineer biology
Harnessing synthetic biology by making promoters for the wide array of chassis organisms used in Industrial Biotech
Creating switches and gene circuits to be employed in any metabolic engineering application
Enable traits discovery
Designing tissue-selective plant synthetic promoters active across different crop species for Agricultural Biotech applications
Using plant genomics to facilitate the design of environmentally-regulated and pathogen-responsive promoters
Science
By studying large genomic datasets, we can discover genomic sequences vital to gene regulation and develop novel, patentable promoters. Understand more about the scientific basis for our approach.
Technology
We have developed a platform of algorithms and know-how that analyses diverse genomics datasets and enables the development of novel sequences that are optimised for specific applications. Discover more about our technology.
Sectors
Precise control of gene expression has applications across cell and gene therapy, biologics manufacturing, industrial biotechnology and agricultural biotechnology.
Cell and Gene
Therapy
Synthetic promoters enable potent cell-selective gene expression and can be designed to respond to different stimuli.
Biologics Manufacturing
Highly active promoters are vital to maximise gene expression and deliver increased yields under specific production conditions.
Industrial Biotechnology
Strong synthetic promoters that are customised to the chassis organism and optimised for expression in the bioreactor.
Agricultural Biotechnology
Precise control over gene expression in specific tissues increases crop yields and protects non-target plant species.
News
Learn more about the latest updates from Chromatin Bioscience.
